Disclosed is an endoscope imaging system and method, which is adapt to display a video inside of a body of a patient. The system includes an endoscope camera module, a video processing module, a memory unit, an analysis module and a display module. The endoscope camera module includes a light source, an IR imaging device, and a video capturing module. The IR imaging device and the video capturing module is configured to shoot a target region and generate a IR image and a visible light image, the analysis module is configured to analysis the IR image to generate at least one emphasis region. The emphasis region is superimposed to the visible light video to generate a superimposition image, which is displayed by the display module.提供一種內視鏡成像系統及方法,適用於顯示一患者體內之影像,其包含內視鏡攝影模組、影像處理模組、記憶單元、分析模組及顯示模組。內視鏡攝影模組包含光源、紅外線成像儀及影像擷取模組。紅外線成像儀及影像擷取模組經配置以拍攝目標區域並產生紅外線及可見光影像訊號。影像處理模組接收紅外線影像訊號及可見光影像訊號並產生紅外線影像及可見光影像,分析模組分析紅外線影像以產生至少一重點區域,並將重點區域疊加至可見光影像以產生疊加影像,並由顯示模組顯示。1‧‧‧內視鏡成像系統100‧‧‧光源102‧‧‧內視鏡攝影模組104‧‧‧紅外線成像儀106‧‧‧影像擷取模組108‧‧‧影像處理模組110‧‧‧記憶單元116‧‧‧分析模組118‧‧‧顯示模組120‧‧‧電源模組