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HBV polymerase mutants
专利权人:
Transgene SA
发明人:
Martin, Perrine,Silvestre, Nathalie,Marchand, Jean-Baptiste
申请号:
AU2012282506
公开号:
AU2012282506A1
申请日:
2012.07.12
申请国别(地区):
AU
年份:
2014
代理人:
摘要:
The present invention relates to polymerase HBV mutant polypeptides comprising a mutated polymerase domain which is functionally disrupted for polymerase activity and fusion proteins comprising such polymerase mutant polypeptide. The present invention also relates to a nucleic acid molecule and an expression vector for expressing said polymerase mutant polypeptide as well as a composition which can be used for eliciting an immune response to HBV with the goal of providing a protective or therapeutic effect against HBV infection.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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