HBV polymerase mutant

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专利权人:

トランジェーヌ、ソシエテ、アノニム

发明人:

ペリーヌ、マルタン,ナタリー、シルベストル,ジャン－バティスト、マルシャン,ジャン-バティスト、マルシャン

申请号：

JP2014519553

公开号：

JP6189293B2

申请日:

2012.07.12

申请国别(地区):

JP

年份:

2017

代理人:

摘要：

The present invention relates to polymerase HBV mutant polypeptides comprising a mutated polymerase domain which is functionally disrupted for polymerase activity and fusion proteins comprising such polymerase mutant polypeptide. The present invention also relates to a nucleic acid molecule and an expression vector for expressing said polymerase mutant polypeptide as well as a composition which can be used for eliciting an immune response to HBV with the goal of providing a protective or therapeutic effect against HBV infection.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/