A method of increasing antimicrobial peptide concentration on the skin is provided. The method includes cleaning skin with at least one of a cleanser and a sanitizer and applying a sanitizing composition to the skin. The sanitizing composition comprises one or more polypeptides and extracts that increase the concentration of antimicrobial peptides. The application also relates to a nasal spray reducing pathogen binding in the nose and comprising a Cl-8 alcohol and one or more of a probiotic, probiotic derivative and a prebiotic.