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COMPLEXES METALLIQUES DE CARBENES N-HETEROCYCLIQUES UTILES COMME PRODUITS RADIOPHARMACEUTIQUES ET ANTIBIOTIQUES
专利权人:
THE UNIVERSITY OF AKRON
发明人:
申请号:
EP04788633.8
公开号:
EP1660444B1
申请日:
2004.09.07
申请国别(地区):
EP
年份:
2014
代理人:
摘要:
A method for inhibiting microbial growth comprises administering an effective amount of a silver complex of a N-heterocyclic amine. A method for treating cancer cells or a method for imaging one or more tissues of a patient includes administering an effective amount of a complex of a N-heterocyclic amine and a radioactive metal. N-heterocyclic carbenes of the present invention may be represented by formula (I) wherein Z is a heterocyclic group, and R<;SUB>;1 <;/SUB>;and R<;SUB>;2 <;/SUB>;are, independently or in combination, hydrogen or a C<;SUB>;1<;/SUB>;-C<;SUB>;12 <;/SUB>;organic group selected from the group consisting of alkyl, cycloalkyl, alkenyl, cycloalkenyl, alkynyl, aryl, arylalkyl, alkylaryl, heterocyclic, and alkoxy groups and substituted derivatives thereof.
来源网站:
中国工程科技知识中心
来源网址:
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