NAGA, KARUN D.,BOYD, STEPHEN W.,RUANE, PATRICK H.,HANCOCK, JACKIE JOE,FELDSTEIN, MICHAEL,TEU, KOON KIAT,WANG, HONGLEI,LUO, JINGNAN,SEET, DANIEL BOON LIM,GIFFORD, HANSON S., III
申请号：
CA3078555
公开号：
CA3078555A1
申请日:
2018.10.06
申请国别(地区):
CA
年份:
2019
代理人:
摘要：
The present technology relates to depots for the treatment of postoperative pain via sustained, controlled release of a therapeutic agent. In some embodiments, the depot may comprise a therapeutic region comprising an analgesic, and a control region comprising a bioresorbable polymer and a releasing agent mixed with the polymer. The releasing agent may be configured to dissolve when the depot is placed in vivo to form diffusion openings in the control region. The depot may be configured to be implanted at a treatment site in vivo and, while implanted, release the therapeutic agent at the treatment site for no less than 3 days.
