Karun D. Naga,Stephen W. Boyd,Patrick H. Ruane,Jackie Joe Hancock,Michael Feldstein,Koot Kiat Teu,Honglei Wang,Jingnan Luo,Daniel Boon Lim Seet,Hanson S. Gifford, III
申请号:
US16840215
公开号:
US20200246255A1
申请日:
2020.04.03
申请国别(地区):
US
年份:
2020
代理人:
摘要:
The present technology relates to depots for the treatment of postoperative pain via sustained, controlled release of a therapeutic agent. In some embodiments, the depot may comprise a therapeutic region comprising an analgesic, and a control region comprising a bioresorbable polymer and a releasing agent mixed with the polymer. The releasing agent may be configured to dissolve when the depot is placed in vivo to form diffusion openings in the control region. The depot may be configured to be implanted at a treatment site in vivo and, while implanted, release the therapeutic agent at the treatment site for no less than 3 days.