Julian C. Rayner;Leyla Y. Bustamante;S. Josefin Bartholdson;Cecile Crosner;Gavin J. Wright
发明人:
Gavin J. Wright,Julian C. Rayner,Cecile Crosner,Leyla Y. Bustamante,S. Josefin Bartholdson
申请号：
US13878149
公开号：
US20140093540A1
申请日:
2011.10.07
申请国别(地区):
US
年份:
2014
代理人:
摘要：
Immunogenic compositions and vaccines against Plasmodial infection comprising an Rh polypeptide or a fragment or variant thereof are disclosed. Also disclosed are Rh5 polypeptides or fragments or variants thereof capable of binding CD147 and conferring protection against infection and/or disease caused by multiple Plasmodial strains or Plasmodial species, inhibitors of the interaction between Rh5 and CD147 and methods for producing polypeptides in a mammalian expression system.
