Gavin J. WRIGHT,Julian C. RAYNER,Cecile CROSNIER,Leyla Y. BUSTAMANTE,S. Josefin BARTHOLDSON
申请号：
US15911816
公开号：
US20180193440A1
申请日:
2018.03.05
申请国别(地区):
US
年份:
2018
代理人:
摘要：
Immunogenic compositions and vaccines against Plasmodial infection comprising an Rh polypeptide or a fragment or variant thereof are disclosed. Also disclosed are Rh5 polypeptides or fragments or variants thereof capable of binding CD147 and conferring protection against infection and/or disease caused by multiple Plasmodial strains or Plasmodial species, inhibitors of the interaction between Rh5 and CD147 and methods for producing polypeptides in a mammalian expression system.
