PROBLEM TO BE SOLVED: To provide a preventing or therapeutic agent which is an inhibitor of a colony-stimulating factor 1 receptor, and is for rheumatoid arthritis, multiple sclerosis, osteoporosis (bone quantity reduction after ovariectomy is included), osteolysis, and cancer (for example, lung cancer and breast cancer).SOLUTION: An azetidine compound represented by general formula [I], a pharmaceutically acceptable salt thereof and a solvate thereof are disclosed.COPYRIGHT: (C)2011,JPO&INPIT【課題】コロニー刺激因子1受容体の阻害剤で、関節リウマチ、多発性硬化症、骨粗しょう症(卵巣摘出後の骨量減少を含む)及び骨溶解、癌(例えば、肺癌、乳癌)の予防又は治療剤の提供。【解決手段】下記一般式[I]で表されるアゼチジン化合物又はその医薬上許容される塩、或いはその溶媒和物。【選択図】なし