PROBLEM TO BE SOLVED: To provide agonists of peroxisome proliferator-activated receptor γ (PPARγ) for treatment of multiple sclerosis (MS).SOLUTION: A method of treating MS comprises administering a therapeutically effective amount of a pharmaceutical composition comprising PPARγ agonists known as INT131 and represented by formula (I) or a pharmaceutically acceptable salt or isomer thereof. The effective dosage of the treatment is from 1 to 3 mg.SELECTED DRAWING: Figure 3【課題】多発性硬化症（ＭＳ）を治療するためのペルオキシソーム増殖因子活性化受容体γ（ＰＰＡＲγ）アゴニストの提供。【解決手段】ＩＮＴ１３１として知られる式（Ｉ）で示されるＰＰＡＲγアゴニスト又はその医薬として許容される塩或いは異性体を含む医薬組成物の治療有効量を投与する、ＭＳを治療する方法。前記治療の有効投与量が１～３ｍｇである医薬組成物。【選択図】図３
