Michael E. Bozik,Thomas Petzinger, Jr.,James L. Mather,Donald Archibald
申请号:
US14194558
公开号:
US09662313B2
申请日:
2014.02.28
申请国别(地区):
US
年份:
2017
代理人:
摘要:
A method for treating amyotrophic lateral sclerosis (ALS) in a subject in need thereof comprising administering to said subject an effective amount of (6R)-2-amino-4,5,6,7-tetrahydro-6-(propylamino)benzothiazole or pharmaceutically acceptable salt thereof, wherein said subject is a treatment responder. In certain embodiments, said subject is a subject with definite amyotrophic lateral sclerosis, a subject with amyotrophic lateral sclerosis symptom onset duration of less than about 18 months, a subject with a high level of serum creatinine, a subject with concomitant riluzole administration and combinations thereof.