CASEBOLT, Brett,MUSSER, Robert, Eldon,HAGEN, Chad, D.
申请号：
EP16747261
公开号：
EP3253405A4
申请日:
2016.02.04
申请国别(地区):
EP
年份:
2018
代理人:
摘要：
Provided herein are methods for altering a characteristic of an offspring or a litter. The method can include administering an effective amount of a composition that includes active IGF-1 to a pregnant animal, wherein a characteristic of an offspring of the pregnant animal is altered compared to a control offspring. In another embodiment, the animal is a lactating animal, wherein a characteristic of an offspring nursed by the lactating animal is altered compared to a control offspring. Examples of characteristics that can be altered include increased survival of offspring before weaning, increased weight of offspring at weaning, increased weight of offspring at end of growing phase, increased average daily gain, and increased average daily food intake. In another embodiment, a characteristic of a litter can be altered, such as increased number of offspring born alive, increased litter birth weight, increased offspring birth weight, reduced number of stillborn offspring, or a combination thereof.
