An EP2 agonist which may have an EP3 agonistic effect has an effect ofregenerating and/or protecting nerves, and is therefore useful as atherapeutic agent for a disease of the peripheral nervous system, such as alower or upper motor neuron disease, a nerve root disease, plexopathy,thoracic outlet compression syndrome, peripheral neuropathy, neurofibromatosisand neuromuscular transmission disease. An EP2 agonist which has an EP3agonistic effect is a safe and effective agent for the regeneration and/orprotection of nerves which has little influence on the circulatory system.
