This invention is related to a material-transporting carrier, an agent comprising the carrier for treating renal fibrosis, manufacturing methods and kits thereof, and a method for treating renal fibrosis with the agent for treating renal fibrosis, wherein the material-transporting carrier comprises retinoid as a targeting agent, and the material-transporting carrier is used for extracellular matrix-synthesizing cells in the renal.本發明是關於一種物質輸送用攜帶體、利用該攜帶體而成之腎纖維症處置劑、這些物質之製造方法、調製套組、及使用該腎纖維症處置劑而進行的腎纖維症之處置方法,其中,該物質輸送用攜帶體,含有類視色素作為標靶藥物,且為腎中的細胞外間質生成細胞用的物質輸送用攜帶體。