The present invention provides an agent for treating skin fibrosis. The agent for treating skin fibrosis comprises a carrier for delivering a substance for the extracellular matrix producing cell in skin, wherein the carrier contains a retinoid.本發明提供一種皮膚纖維化治療劑。本發明是一種皮膚中的細胞外間質生成細胞用的物質輸送攜帶體,該物質輸送攜帶體包含類視色素;及,一種利用該攜帶體之皮膚纖維化症治療劑。