Sorafenib salts

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专利权人:

EGIS GYOGYSZERGYAR NYILVANOSAN MUEKOEDOE RESZVENYTARSASAG

发明人:

KIRALY IMRE,HEDER JANOS LEVENTE,GREGOR TAMAS,VOLK BALAZS,TOTHNE LAURITZ MARIA,PONGO LASZLO,BUETE KATALIN,LUKACS GYULA,VARGA ZOLTAN,DANCSO ANDRAS

申请号：

HU1300504

公开号：

HU1300504A2

申请日:

2013.08.27

申请国别(地区):

HU

年份:

2015

代理人:

摘要：

The invention relates to novel (1:1) salts of sorafenib and the hydrate and solvate forms thereof. More specifically the invention concerns: - the sorafenib hydrogen-bromide (1:1) monoacetonitrile solvate salt, - the sorafenib hydrogen-bromide (1:1) hemihydrate salt, - the sorafenib naphthalene-2-sulfonic acid (1:1) anhydrous (form I, II and III) salt, - the sorafenib naphthalene-2-sulfonic acid (1:1) monoethanol solvate salt. Moreover the invention relates to preparing the mentioned sorafenib salts, pharmaceutical compositions comprising them for the treatment of carcinoma.

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中国工程科技知识中心

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