Combination of a) olodaterol, its individual R-optical isomer, mixtures of individual enantiomers or racemates, acid addition salts thereof with pharmacologically acceptable acids, optionally in the form of solvates and / or hydrates, and b) a tiotropium salt； in particular a combination of a) olodaterol and acid addition salts thereof with pharmacologically acceptable acids, and b) tiotropium bromide, optionally in the form of a solvate and / or hydrate； more in particular combination of a) olodaterol hydrochloride and b) tiotropium bromide, optionally in the form of the monohydrate
A composition comprises at least one 6-hydroxy-4H-benzo[1,4]oxazin-3-one derivative and at least one other active substance. A composition comprises at least one 6-hydroxy-4H-benzo[1,4]oxazin-3-one compounds of formula (I) and at least one other active substance. n : 1 or 2； R 1 and R 2 : H, halo, 1-4C alkyl or -O-1-4C alkyl；and R 3 : 1-4C alkyl, OH, halo, -O-1-4C alkyl, -O-1-4C alkylene-COOH or -O-1-4C alkylene-CO-O-1-4C alkyl. [Image] ACTIVITY : Antiinflammatory； Respiratory-Gen.； Antiasthmatic； Dermatological； Immunosuppressive； Antiallergic； Cardiant； Vasotropic. MECHANISM OF ACTION : None given.
