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Methods of Managing Graft Versus Host Disease (GvHD) Using Indole Carboxyaldehydes or Derivatives Thereof
专利权人:
发明人:
Daniel Kalman,Edmund K. Waller,Cynthia R. Giver,Alyson Swimm,Sravanti Rangaraju
申请号:
US15268577
公开号:
US20170079950A1
申请日:
2016.09.17
申请国别(地区):
US
年份:
2017
代理人:
摘要:
In certain embodiments, this disclosure relates to methods of treating or preventing HvGD comprising administering an effective amount of indole-2-carboxyaldehyde, indole-3-carboxyaldehyde, or derivative to a subject in need thereof. In certain embodiments, this disclosure relates to methods of treating a subject with a hematological malignancy or other cancer comprising transplanting allogenic bone marrow or stem cells in combination with administering an effective amount of an indole-2-carboxyaldehyde, indole-3-carboxyaldehyde, or derivative thereof to a subject in need thereof.
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