USE OF BRADYCARDIAC SUBSTANCES IN THE TREATMENT OF MYOCARDIAL DISEASES ASSOCIATED WITH HYPERTROPHY AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM

• 收藏
• 分享

专利权人:

BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG

发明人:

DAEMMGEN, JUERGEN,GUTH, BRIAN,SEIDLER, RANDOLPH

申请号：

HU0300917

公开号：

HU228387B1

申请日:

2001.04.07

申请国别(地区):

HU

年份:

2013

代理人:

摘要：

A medicament (A) for treating myocardial diseases associated with hypertrophy contains a bradycardic agent (I) and optionally another cardiac drug (II). ACTIVITY : Cardiant. In tests in a cat having severe hypertrophic cardiomyopathy, oral administration of cilobradine (Ia) twice daily at 0.3 mg/kg marked reduced the clinical symptoms (e.g. by reducing pain and normalizing the ECG) and also caused regression of the myocardial hypertrophy after 1 and 2 years. MECHANISM OF ACTION : Calcium ion channel blocker； beta -receptor blocker； i f channel blocker.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/