DAEMMGEN JUERGEN,JÜRGEN DÄMMGEN,GUTH BRIAN,BRIAN GUTH,SEIDLER RANDOLPH,RANDOLPH SEIDLER,DÄMMGEN JÜRGEN
申请号：
PL357827
公开号：
PL215235B1
申请日:
2001.04.07
申请国别(地区):
PL
年份:
2013
代理人:
摘要：
A medicament (A) for treating myocardial diseases associated with hypertrophy contains a bradycardic agent (I) and optionally another cardiac drug (II). ACTIVITY : Cardiant. In tests in a cat having severe hypertrophic cardiomyopathy, oral administration of cilobradine (Ia) twice daily at 0.3 mg/kg marked reduced the clinical symptoms (e.g. by reducing pain and normalizing the ECG) and also caused regression of the myocardial hypertrophy after 1 and 2 years. MECHANISM OF ACTION : Calcium ion channel blocker； beta -receptor blocker； i f channel blocker.
