The invention provides an astaxanthin complex and the application on regulating the lipid profile, a preparation system and a method of preparing astaxanthin complex. The astaxanthin complex comprises powder ofHaematococcus Pluvialis, extract of wolfberry, extract of wolfberry, and arginine. The system includes a mixing unit and an additive-adding unit, those which operate sequentially to prepare a compound astaxanthin complex, the invention thus provides a stable and sustainably active compound astaxanthin complex with long shelf-life, which can bring favorable effects on regulating the lipid profile.本發明提供一種蝦紅素複方組合物及其製備系統與方法,蝦紅素複方組合物包含紅球藻組成物、枸杞萃取物、紅棗萃取物以及精氨酸;製備系統包含混合單元、添加單元,循序操作以製備蝦紅素複方組合物;方法上包含混合步驟以及添加步驟,循序執行以製備前述之蝦紅素複方組合物,使成品性質安定、活性效期長、耐儲放,並具調節血脂之功效。