The present invention relates to key genes in the biosynthesis of animal milk proteins and to genetically modified or gene edited plants with altered content of animal milk proteins, particularly to plants with de novo production content of animal milk proteins and any of their derivatives. Additionally, the present invention relates to a DNA binary vector or viral vector for expressing in a plant, proteins from the milk of a mammal; to a genetically modified or gene-edited plant having at least one cell expressing at least two recombinant protein from the milk of a mammal and expressed in the genetically modified or gene-edited plant or a seed, bean, grain, fruit, nut, legume, leaf, stem, root, or portion thereof, the recombinant protein being produced by the plant cell; and to a method of producing a food, medicament, cosmetic or blocking composition from the genetically modified or gene-edited plant. The present invention also relates to plant- based food, medicament, cosmetic or blocking compositions comprising animal milk proteins and methods of making the same. The present invention also relates to the reduction or elimination of seed storage proteins in a cell or cells wherein the milk proteins are introduced, or reduction of plant enzymes that can increase the content of oleic and/or stearic fatty acids and/or reduce the content of saturated fats in said plants or plant products.La présente invention concerne des gènes clés dans la biosynthèse de protéines de lait animal et des plantes génétiquement modifiées ou d'édition génique ayant une teneur modifiée en protéines de lait animal, en particulier des plantes ayant un contenu de production de novo de protéines de lait animal et l'un quelconque de leurs dérivés. De plus, la présente invention concerne un vecteur viral ou vecteur binaire à ADN pour exprimer dans une plante, des protéines à partir du lait d'un mammifère ; une plante génétiquement modifiée ou d'édition génique ayant au moins une cellule exprima