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PREPARATION METHOD FOR MEDICAL POROUS METAL MATERIAL FOR WEIGHT-BEARING BONE TISSUE REPLACEMENT
专利权人:
CHONGQING RUNZE PHARMACEUTICAL COMPANY LIMITED.
发明人:
YE, Lei,叶雷
申请号:
CNCN2012/082084
公开号:
WO2013/044809A1
申请日:
2012.09.26
申请国别(地区):
WO
年份:
2013
代理人:
摘要:
A preparation method for a medical porous metal material for weight-bearing bone tissue replacement comprising: mixing tantalum powder, a pore-forming agent, and a forming agent, press-forming the powder mixture into an organic foamed body, then degreasing, sintering, cooling, and performing a heating process. The pressure during the press-forming is 50 to 100 Mpa. The degreasing process comprises: gradually increasing the temperature to 400 to 800°C at a speed of 0.3 to 2°C/min, introducing argon gas to form a protective atmosphere, and maintaining the temperature for 300 to 360 minutes. The pore-forming agent is ammonium bicarbonate or hydrogen peroxide. The forming agent is one or multiple of stearic acid, zinc sterate, paraffin, and synthetic resin. Within a vacuum degree of 10-4 to 10-3 Pa, increasing the temperature to 800 to 900°C at a speed of 10 to 20°C/min, maintaining the temperature for 240 to 480 minutes, cooling to 400°C at a speed of 2 to 5°C/min, maintaining the temperature for 120 to 300 minutes, and cooling together with the furnace to room temperature. Measurements show that the impurity concentration thereof is lower than 0.2%. The density reaches 6.67 to 8.34 g/cm3, the porosity reaches 50% to 60%, and the pore diameter reaches 150 to 450 μm. The elastic modulus reaches 4.5 to 6.0 Gpa, and the bending strength reaches 100 to 120 Mpa.Procédé de préparation dun matériau métallique poreux à usage médical de substitution dun tissu osseux de support, selon lequel la poudre de tantale est mélangée avec lagent de formation de pores et lagent moulant, la poudre ainsi mélangée est comprimée jusquà obtenir, dans un corps mousseux organique, le moulage, décrassage, frittage, refroidissement et traitement thermique, la pression étant comprise entre 50 et 100 MPa, le décrassage seffectuant à une température augmentant graduellement de 400 à 800°C, de telle sorte que largon forme une atmosphère protectrice et conserve la température comprise entre 300 et 360°
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