HO, SOO YEI,BLANCHARD, STEPHANIE ELIANE,DURAISWAMY, ATHISAYAMANI JEYARAJ,ALAM, JENEFER,ADSOOL, VIKRANT ARUN
申请号:
EP14801575
公开号:
EP2999699A4
申请日:
2014.05.19
申请国别(地区):
EP
年份:
2016
代理人:
摘要:
The invention relates to the use of compounds of general structure (I) in modulation of the Wnt pathway [Formula should be inserted here] wherein R1, R2, R3, R4 and R5 are each, independently, H or an alkyl group; D is selected from the group consisting of H, halogen, alkyl, cycloalkyl, aryl, and dialkylamino, each (other than H and halogen) being optionally substituted; Ar is an aryl or heteroaryl group, optionally substituted; Cy is an aryl, heteroaryl or a saturated ring containing at least one heteroatom, each being optionally substituted; and n is an integer from 1 to 3.