Devices and methods are provided for selecting a location to implant an electrode as part of a baroreflex activation therapy system. Images of a target blood vessel may be obtained with an imaging device, and the image used as part of or in conjunction with a patient-response-mapping procedure to determine a favorable location on the blood vessel to implant the electrode. Alternately, temperature measurements may be taken of a target vessel and utilized as part of or in conjunction with a patient-response-mapping procedure to determine a favorable location on the blood vessel to implant the electrode.
