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作為組蛋白脱甲基酶抑制劑的取代的(E)-N'-(1-苯基亞乙基)苯甲酰肼類似物
专利权人:
UNIVERSITY OF UTAH RESEARCH FOUNDATION
发明人:
VANKAYALAPATI, HARIPRASAD,SORNA, VENKATASWAMY,WARNER, STEVE, L. L,BEARSS, DAVID, J. J,SHARMA, SUNIL,STEPHENS, BRET,蘇尼爾.沙瑪,布雷特.史蒂芬斯,哈里普拉薩德.梵卡亞拉帕提,文卡塔斯瓦米.索爾那,史蒂夫.,.華納,大衛.,.比爾斯,蘇尼爾.沙瑪,布雷特.史蒂芬斯
申请号:
HK15100490.8
公开号:
HK1200052A
申请日:
2015.01.15
申请国别(地区):
HK
年份:
2015
代理人:
摘要:
In one aspect, the invention relates to substituted (E)-N′-(1-phenylethylidene)benzohydrazide analogs, derivatives thereof, and related compounds, which are useful as inhibitors of lysine-specific histone demethylase, including LSD1; synthetic methods for making the compounds; pharmaceutical compositions comprising the compounds; and methods of using the compounds and compositions to treat disorders associated with dysfunction of the LSD1. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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