PARK, Jun Seong,PARK, Hye Yoon,KIM, Dong Hyun,LEE, Sang Min,SHIN, Dong Wook,KIM, Shin Hyoung,NOH, Min Soo,KIM, Duck Hee,KIM, Han Kon
申请号：
EP09827701
公开号：
EP2349254B1
申请日:
2009.11.17
申请国别(地区):
EP
年份:
2018
代理人:
摘要：
Disclosed herein is a skin external composition for inhibiting epidermal hyperproliferation and alleviating inflammatory skin diseases, which contains ortho-dihydroxyisoflavone derivatives as an active ingredient. Specifically, the skin external external composition contains the ortho-dihydroxyisoflavone derivatives, 4&prime,6,7-trihydroxyisoflavone, 3&prime,4&prime,7-trihydroxyisoflavone or a mixture thereof, and thus increases the expression of DKK3 protein and FZD1 protein, which appropriately control Wnt signaling, thereby inhibiting epidermal hyperproliferation and alleviating inflammatory skin diseases caused by epidermal hyperproliferation.
