Composition for diagnosing, preventing or treating diseases associated with IL-8 or GRO-α expressing cells, including umbilical cord blood-derived mesenchymal stem cells

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专利权人:

メディポスト・カンパニー・リミテッド

发明人:

チャン ヨン ウー,キム ダル－ソー,ヤン ユン－スン,オウ ウォン イル,キム ダル-ソー,ヤン ユン-スン

申请号：

JP2010522804

公开号：

JP5529021B2

申请日:

2008.08.27

申请国别(地区):

JP

年份:

2014

代理人:

摘要：

Provided is a gene therapy composition for transferring one of a therapeutic gene, a maker gene, or a mixture thereof to a cell that expresses interleukin-8 (IL-8) or GRO-alpha and induces tropism of mesenchymal stem cells isolated from umbilical cord blood and/or the mesenchymal stem cells expanded from said mesenchymal stem cells (UCB-MSCs), wherein the cell-treating composition includes UCB-MSCs. Provided is a composition for treating disease related to a cell expressing IL-8 or GRO-alpha, that is, a brain tumor in gene therapy, by using UCB-MSCs. Provided is a composition or kit for diagnosing brain tumors, preventing brain tumors, treating brain tumors, or monitoring brain tumor treatment progression by using UCB-MSCs.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/