An opening device (1) for acting onto a closure element (70, 71) of a medical tubing (7), comprises a housing (10), an opening mechanism (2) arranged in or on the housing (10) for acting onto a closure element (70, 71) of a tubing (7) for opening a flowpath (F) within the tubing (7), and a drive arrangement (6) for driving the opening mechanism (2). Herein, the opening mechanism (2) comprises a first tube reception device (A1) and a second tube reception device (A2), the first tube reception device (A1) and the second tube reception device (A2) each being constituted to receive a medical tubing (7) for acting onto a closure element (70, 71) of the tubing, wherein the opening mechanism (2) is displaceable relative to the housing (10) between a first position in which a tubing (7) is insertable into the first tube reception device (A1) and a second position in which a tubing (7) is insertable into the second tube reception device (A2). In this way an opening device is provided which in an easy-to-use manner allows for opening closure elements of different kinds.Un dispositivo de abertura (1) para actuar sobre un elemento de cierre (70, 71) de un tubo médico (7), que comprende un alojamiento (10), un mecanismo de abertura (2) que se coloca en o sobre el alojamiento (10) para actuar en un elemento de cierre (70, 71) de un tubo (7) para abrir una trayectoria de flujo (F) dentro del tubo (7), y una disposición de accionamiento (6) para accionar el mecanismo de abertura (2) en la presente, el mecanismo de abertura (2) comprende un primer dispositivo de recepción del tubo (A1) y un segundo dispositivo de recepción del tubo (A2), el primer dispositivo de recepción del tubo (A1) y el segundo dispositivo de recepción del tubo (A2) cada uno está constituido para recibir un tubo médico (7) para actuar sobre un elemento de cierre (70, 71) del tubo, en donde el mecanismo de abertura (2) se desplaza con respecto al alojamiento (10) entre una primera posición en donde un tubo (7) se