The present disclosure provides stents, particularly self-expanding stents, useful for the GI tract, and more particularly, useful for treating esophageal strictures. The stents provided herein include a medial region and proximal and distal cuffs having external diameters greater than the medial region diameter when the stent is in the deployed state. The medial region comprises an open weave wire construction. An elastomeric coating circumscribes the medial region, while the may be an extension of the wire construction or separate elements. Preferably, the cuffs have a textured surface for contact with the esophageal wall tissue to resist stent migration. The elastomer coated medial region provides a barrier to tissue ingrowth, and has an enhanced radial restoring force to maintain an open passageway in a body lumen. Optionally, the stent includes an exterior sheath with a surface pattern, to which the stent couples. A low durometer sleeve, between the stent and body lumen, axial positioning of the stent relative to the body lumen. Consequently, precision in stent placement is provided without tissue damage that could result if positioning motion occurred between the surface texture and the body lumen.本發明提供支架，特別地，自擴張式支架，可用於胃腸(GI)道，且更特別地，可用於治療食道狹窄。在本文中所提供的支架可包含中間區域及近端和遠端環帶，當該支架係在部署狀態之中時，該近端和遠端環帶具有比該中間區域的直徑更大的外徑。該中間區域包含開放式編織線結構。彈性體塗層外接該中間區域，且同時，它們可係該線結構的延伸或單獨的元件。較佳地，該等環帶具有用於與食道壁組織接觸的紋理表面，用以阻擋支架移位。彈性體塗層的中間區域為組織之向內成長提供了障壁，以及具有強化的徑向恢復力，用以在體腔中維持開放的通道。選項地，支架包含該支架耦接之具有表面圖案的外部護套。低硬度的護套在支架與體腔之間，該支架相對於體腔而軸向地定位。因此，提供了在支架放置中的精度而沒有如果在表面紋理與體腔之間發生定位運動時可能導致的組織損傷。
