您的位置: 首页 > 农业专利 > 详情页

ANTIBODY DRUG
专利权人:
МЕДИММУН; ЛЛК (US)
发明人:
Стивен БИШОП (US),Дженни С. УОЛФОРД (US)
申请号:
RU2013121156/10
公开号:
RU2013121156A
申请日:
2013.05.08
申请国别(地区):
RU
年份:
2014
代理人:
摘要:
1. A sterile, stable aqueous preparation comprising an antibody or fragment thereof that specifically binds to human α-interferon. The drug according to claim 1, where the specified antibody or its fragment was not subjected to lyophilization. The preparation according to claim 1, wherein said antibody or fragment thereof is an immunoglobulin selected from the group consisting of immunoglobulins such as IgA, IgE, IgM, IgD, IgY and IgG. The preparation according to claim 1, wherein said antibody or fragment thereof is an isotype of human IgG1, IgG2, IgG3 or IgG4. The preparation according to claim 1, wherein said antibody or fragment thereof is a murine antibody or fragment thereof, a hybrid antibody or fragment thereof, a humanized antibody or fragment thereof, or a human antibody or fragment thereof. The preparation according to any one of claims 1 to 5, wherein said antibody or fragment thereof comprises a heavy chain variable sequence of SEQ ID NO: 1.7. A preparation according to any one of claims 1 to 5, wherein said antibody or fragment thereof comprises a light chain variable sequence of SEQ ID NO: 2.8. The preparation according to any one of claims 1 to 5, wherein said antibody or fragment thereof comprises a heavy chain variable sequence of SEQ ID NO: 1 and a light chain variable sequence of SEQ ID NO: 2.9. A preparation according to any one of claims 1 to 5, wherein said antibody is a 13H5 antibody specific for human α-interferon. The drug according to claim 1, where the concentration of the indicated antibody or its fragment is at least 50 mg / ml, at least 60 mg / ml, at least 70 mg / ml, at least 80 mg / ml, at least 90 mg / ml, at least 100 mg / ml, at least 120 mg / ml, at least 150 mg / ml, at least 160 mg / ml, at least 180 mg / ml, at least1. Стерильный стабильный водный препарат, включающий антитело или его фрагмент, который специфично связывается с α-интерфероном человека.2. Препарат по п.1, где указанное антитело или его фрагмент не подвергались
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

意 见 箱

匿名:登录

个人用户登录

找回密码

第三方账号登录

忘记密码

个人用户注册

必须为有效邮箱
6~16位数字与字母组合
6~16位数字与字母组合
请输入正确的手机号码

信息补充