Being method for occurrence prevention or remedy of the Gv HD complication in the mammalian patient, in Mammalia, the STRO 1bright cell and/or in that descendant enriched the cell population which is done and/or the method of including the fact that solubility factor of that origin is prescribed.哺乳類患者におけるGv HD合併症の発生予防または治療のための方法であって、哺乳類に、STRO-1bright細胞および/もしくはその子孫に富化された細胞集団並びに/またはそれ由来の可溶性因子を投与することを含む方法。