A compound having the formula: ** Formula ** in which -GHJ, alternatively, is ** Formula ** in which each H and J are independently selected, D and E are single bonds and F is hydrogen, CBA - and -GHJ are chemical moieties, in which A is selected from (a) a 3-14 membered saturated, unsaturated or aromatic heterocycle containing one or more heteroatoms selected from the group consisting of nitrogen and sulfur, and (b) a 3-14 membered saturated, unsaturated or aromatic carbocycle, in which (a) or (b) is optionally substituted with one or more R5 groups； G is (a) a 3-14 membered saturated, unsaturated or aromatic heterocycle containing one or more heteroatoms selected from the group consisting of nitrogen, oxygen and sulfur, or (b) a 3-14 saturated, unsaturated or aromatic carbocycle members, in which (a) or (b) is optionally substituted with one or more R5 groups； H is selected from the group consisting of: (a) a single bond； (b) a 3-14 membered saturated, unsaturated or aromatic heterocycle containing one or more heteroatoms selected from the group consisting of nitrogen, oxygen and sulfur, (c) a 3-14 membered saturated, unsaturated or aromatic carbocycle in which (b) or (c) is optionally substituted with one or more R5 groups； (d) - (C1-8alkyl) -, (e) - (C2-8alkenyl) -, (f) - (C2-8alkynyl) -, where i) 0-4 carbon atoms in any of (d) - (f) immediately above are optionally replaced by a residue selected from the group consisting of -O-, -S (O) p-, -NR6-, - (C>； = O) -, - C (>； = NR6) -, -S (O) pNR6-, -NR6S (O) p-, and NR6S (O) pNR6-, ii) any of (d) - (f) immediately above is optionally substituted with one or more groups R5, and iii) any of (d) - (f) immediately above is optionally substituted with groups - (C1-8 alkyl) -R5； and (g) - (CR6R6) t-, B is (a) - (C1-8 alkyl) -, (b) - (C2-8 alkenyl) -, (c) - (C2-8 alkynyl) -, or (d) a single bond, where i) 0-4 carbon atoms in any of (a) - (c) immediately above are optionally replaced by a residue selected from the group
