MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG
发明人:
WALD, MARTIN,CROMWELL, OLIVER,NANDY, ANDREAS,KAHLERT, HELGA,WEBER, BERNHARD,FIEBIG, HELMUT
申请号:
CA2528053
公开号:
CA2528053C
申请日:
2004.05.06
申请国别(地区):
CA
年份:
2014
代理人:
摘要:
The invention relates to the production and use of variants of the group 5allergens of Pooideae, characterised in displaying a reduced IgE reactivityrelative toknown wild type allergens and also a substantially retained reactivity with T-lymphocytes.Said hypoallergenic allergen varieties can be used for specificimmunotherapy (hyposensitisation) of patients with grass pollen allergies orforpreventative immunotherapy of grass pollen allergies.