The present invention includes compositions for treating a lysosomal storage disease or disorder, and methods using same. In certain embodiments, the compositions of the invention comprise a histone deacetylase inhibitor (HDACi), a cyclodextrin, water, optionally a polyalkylene glycol, and optionally dimethyl sulfoxide (DMSO). In other embodiments, the compositions of the invention comprise a HDACi, a cyclodextrin, water, a polyalkylene glycol, and DMSO.
