GARCIA - MARTINEZ, LEON,JENSEN, ANNE ELISABETH CARVALHO,OLSON, KATIE,DUTZAR, BEN,LATHAM, JOHN,KOVACEVICH, BRIAN,SMITH, JEFFREY T
申请号:
NZ59251609
公开号:
NZ592516A
申请日:
2009.11.24
申请国别(地区):
NZ
年份:
2013
代理人:
摘要:
Disclosed are therapeutic methods using IL-6 antagonists such as an Ab 1 antibody or antibody fragment having binding specificity for IL-6 to prevent or treat disease or to improve survivability or quality of life of a patient in need thereof Patients will preferably comprise those exhibiting (or at risk of developing) an elevated serum C-reactive protein level, reduced serum albumin level, elevated D-dimer or other coagulation cascade related protein(s), cachexia, fever, weakness and/or fatigue prior to treatment The subject therapies also may include the administration of other actives such as chemotherapeutics, anti-coagulants, statins, and others.