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IL-6 antagonists for preventing or treating thrombosis
专利权人:
アルダーバイオ ホールディングス エルエルシー
发明人:
スミス、ジェフリー、ティー.エル.,スミス、ジェフリー、ティー.エル.
申请号:
JP2015106107
公开号:
JP6050431B2
申请日:
2015.05.26
申请国别(地区):
JP
年份:
2016
代理人:
摘要:
The present invention is directed to therapeutic methods using IL-6 antagonists such as an Abl antibody or antibody fragment having binding specificity for IL-6 to prevent or treat disease or to improve survivability or quality of life of a patient in need thereof. In preferred embodiments these patients will comprise those exhibiting (or at risk of developing) an elevated serum C-reactive protein level, reduced serum albumin level, elevated D-dimer or other coagulation cascade related protein(s), cachexia, fever, weakness and/or fatigue prior to treatment. The subject therapies also may include the administration of other actives such as chemotherapeutics, anti-coagulants, statins, and others.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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