Berislav V. Zlokovic,Alaka Srivastava,Rashid Deane
申请号：
US13501877
公开号：
US20120201757A1
申请日:
2010.10.18
申请国别(地区):
US
年份:
2012
代理人:
摘要：
A mutant low-density lipoprotein receptor related protein-1 binds to Alzheimer amyloid-beta (Aβ) peptide with greater affinity compared to its wild-type homolog. This binding may be used to detect Aβ or to separate Aβ from the rest of a subjects body. In Alzheimer disease, it may be used to provide diagnostic results by detecting Aβ, treatment by removing Aβ, or both.
