Piperidine derivatives or pharmaceutically acceptable salts thereof

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专利权人:

アステラス製薬株式会社;壽製薬株式会社

发明人:

菊池 和美,藤安 次郎,渡辺 俊博,永倉 透記,冨山 泰,曽根川 元治,徳嵜 一夫,岩井 辰憲

申请号：

JP2006532764

公开号：

JP5025266B2

申请日:

2005.08.31

申请国别(地区):

JP

年份:

2012

代理人:

摘要：

The piperidine derivative of the present invention in which the 4-position of the piperidine ring is bonded, via vinylene, to a mono-substituted (-R 1 ) or unsubstituted benzene ring and the 1-position of the piperidine ring has an acyl group [-C(=O)-R 4 ], or a pharmaceutically acceptable salt thereof has an excellent sodium channel inhibition action and an excellent analgesic action and shows a high analgesic effect particularly to neurogenic pain. The present compound is useful as a sodium channel inhibitor of low side effect

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