1. This compound is an equation compound (1) with high affinity and activity on the A2D subunit of voltage activated calcium channel (VGCC),O dual activity to the A2D subunits of VGCC and net. The procedure for the preparation of these compounds and the composition of these compounds and their use as drugs are also discussed. 1. Claim 1: it consists of general formula (1),1. R1 is a radical c8327c833183268ramido o no ramido o o halogeoqui c8328331836262；R2. Is an arilo composed of six selective members, which is composed of halogen atom, c83218318332628ramido or no ramido, alcocilo c831833183226ramido or no ramido, haloalcoxyl c83183318332626a；a. A c83216c8331832626 or a hydrocarbon radical； or a 5 or 6-member heteromorphic group, in which at least one heteromorphic atom is selected from n, O and S； N and m are independent of 0 or 1； Z1 and Z o are independent of one hydrogen atom； a c83183318326ramiabeo or ramiabeo free radical tar； a halogen atom； a halogen atom； a halogen atom； a halogen atom； a halogen atom； a halogen atom； a halogen atom； a halogen atom； a halogen atom； a halogen atom； a halogen atom； a halogen atom； a halogen atom； a halogen atom； a halogen atom； a halogen atom； a halogen atom； a halogen atom； a.Radical alcoxilo C83218D31832626；radical cyclo-c83238D8331832626；a. The invention relates to a c833218c831832626；a. One halogenated alcoxyl radial c8321c 8331832626；W-r3 was in the target or expected position； W - (ch83222) - 8346； -；-C（o）-；Or link； P is 1 or 2； R3 is the wreckage (2) of a set of formulas,2. Y1 and 2 are independent - ch832222-o-c (o)；Y3 ES-CHR8311A-O-C（O）-；-YS-8308ES-CH-O-N-R8310A；e. R83088 and r83099 are independent hydrogen atoms, c83218331832626 are isomerized or non isomerized radical tar, or radical - (c8322832q) q-nrr, where q is 0 or 1, R and R 'are independent hydrogen atoms or c83218331832626 are isomerized or non isomerized radical tar； 1 or 2 of a, B and D, representing - N and other artificial - CH；E stands for n-o-ch；R831
