Ernesto Jorge PODESTA,Paula Mariana MALOBERTI,Ulises Daniel ORLANDO,Melina Andrea DATTILO,Ana Fernanda CASTILLO,Angela Rosaria SOLANO
申请号:
US15058916
公开号:
US20160303090A1
申请日:
2016.03.02
申请国别(地区):
US
年份:
2016
代理人:
摘要:
The present invention relates to compositions and methods for preventing and treating cell proliferation in cancer. More specifically, the present invention relates to compositions and methods for inhibiting tumor growth, and for treating proliferative diseases, particularly colon and breast cancer, with a combined pharmacological approach. Yet more specifically, the compositions for inhibiting tumor growth comprise a combination of: i) a first component which is an ACSL4 inhibitor and ii) a second component selected from the group consisting of mTOR inhibitor and ER inhibitor.