Keith Wilcoxen,Alexander Gutin,Kirsten Timms,Victor Abkevich,Yan Wang,Jerry Lanchbury
申请号:
US14962588
公开号:
US20160160294A1
申请日:
2015.12.08
申请国别(地区):
US
年份:
2016
代理人:
摘要:
This document provides methods and materials involved in assessing samples (e.g., cancer cells) for the presence of homologous recombination deficiency (HRD) or an HRD signature to predict response to niraparib. For example, methods and materials for determining whether or not a cell (e.g., a cancer cell) contains an HRD signature to predict response to niraparib are provided.