Polypeptide, nucleic acid sequence encoding such a polypeptide and the use of such a polypeptide in the preparation of a medicament for suppressing cancer
KEITH FOSTER;SYNTAXIN LIMITED;FREDERIC MADEC;PHIL LECANE;PHILIP MARKS
发明人:
PHILIP MARKS,KEITH FOSTER,FREDERIC MADEC,PHIL LECANE
申请号：
IL20985410
公开号：
IL209854A
申请日:
2010.12.08
申请国别(地区):
IL
年份:
2013
代理人:
摘要：
The present invention relates to a method for suppressing or treating cancer, in particular to a method for suppressing or treating one or more of colorectal cancer, breast cancer, prostate cancer and/ or lung cancer. The therapy employs use of a non-cytotoxic protease, which is targeted to a growth hormone-secreting cell such as to a pituitary cell. When so delivered, the protease is internalised and inhibits secretion/ transmission of growth hormone from said cell. The present invention also relates to polypeptides and nucleic acids for use in said methods.
