The disclosure generally relates to dual-energy imaging, and in particular, techniques to produce and process dual-energy images using a dual-energy imaging system. One embodiment provides a method for generating at least one image of a region of interest in a patient, the method comprising: obtaining at least two radiological images of the region of interest identified with at least one marker arranged on and/or around the patient, wherein a first image is acquired with a first X-ray energy and a second image is acquired with a second X-ray energy and determining a final radiological image of the region of interest by linearly combining the two radiological images to obtain an image without the markers.
