ATROPINE SULFATE RAPIDLY-DISINTEGRATING SUBLINGUAL TABLETS, METHODS FOR MANUFACTURE THEREOF, AND METHODS FOR USE THEREOF FOR TREATMENT OF ACUTE ORGANOPHOSPHATE TOXICITY

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专利权人:

NOVA SOUTHEASTERN UNIVERSITY

发明人:

Mutasem Rawas-Qalaji,Alhussain H. Aodah

申请号：

US15516444

公开号：

US20170246158A1

申请日:

2015.10.02

申请国别(地区):

US

年份:

2017

代理人:

摘要：

The invention provides atropine sulfate (AS) rapidly-disintegrating sublingual tablets (RDSTs) in a sublingual dosage form and methods for therapeutic use of the AS RDSTs for treatment of organophosphate (OP) exposure and acute toxicity. The AS RDSTs provide an alternative easy-to-use dosage form for the management of organophosphate toxicity. Additionally, the invention provides methods for formulation and quality evaluation of the atropine sulfate rapidly-disintegrating sublingual tablets.

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