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DERIVE HETEROCYCLIQUE FUSIONNE, COMPOSITION MEDICALE LE CONTENANT ET UTILISATION MEDICALE ASSOCIEE
专利权人:
KISSEI PHARMACEUTICAL CO.; LTD.
发明人:
FUSHIMI, NOBUHIKO,YONEKUBO, SHIGERU,MURANAKA, HIDEYUKI,SHIOHARA, HIROAKI,TERANISHI, HIROTAKA,SHIMIZU, KAZUO,ITO, FUMIAKI,ISAJI, MASAYUKI
申请号:
CA2520436
公开号:
CA2520436C
申请日:
2004.03.24
申请国别(地区):
CA
年份:
2012
代理人:
摘要:
The present invention provides fused heterocyclicderivatives represented by the general formula:(see formula I)wherein R1 represents H, halogen, OH, etc.; R2 represents H,halogen or an alkyl group; R3 and R4 represent H, OH, halogen,etc.; Q represents alkylene, etc.; ring A represents aryl orheteroaryl; and G represents(see formula G1)or(see formula G2)or pharmaceutically acceptable salts thereof, or prodrugsthereof, which exhibit an excellent inhibitory activity in humanSGLT and are useful as agents for the prevention or treatmentof a disease associated with hyperglycemia such as diabetes,postprandial hyperglycemia, impaired glucose tolerance,diabetic complications or obesity, pharmaceutical compositionscomprising the same, and pharmaceutical uses thereof.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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