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A FUSED HETEROCYCLE DERIVATIVE AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME
专利权人:
发明人:
FUSHIMI NOBUHIKO,ISAJI MASAYUKI,FUJIKURA HIDEKI
申请号:
IN5059/DELNP/2006
公开号:
IN251968B
申请日:
2006.09.01
申请国别(地区):
IN
年份:
2012
代理人:
摘要:
The present invention provides fused heterocyclic derivatives represented by the following general formula (I) or pharmaceutically acceptable salts thereof, or prodrugs thereof, which exhibit an inhibitory activity in human SGLT and are useful as agents for the prevention or treatment of a disease associated with hyperglycemia such as diabetes, postprandial hyperglycemia, impaired glucose tolerance, diabetic 1 4 complications or obesity, in the formula R1 to R4 represent H, OH, an amino group, etc. R5 and R6 represent H, OH, a halogen atom, an optionally substituted alkyl group, etc. Q represents alkylene, alkenylene, etc. ring A represents an aryl group or a heteroaryl group the following ring (Rl) represents a group represented by the following ring (R2) G represents a group represented by the following general formula (G-l) or (G-2) (E1 2 represents H, F or OH and E2 represents H, F, a methyl group, etc.), and pharmaceutical compositions comprising the same, and pharmaceutical uses thereof.
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