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Cycloalkylamne derivatives
专利权人:
Shinji Marumoto;Yasuo Fukushima;Mikio Kato;Masayuki Ebisawa;Toyoki Nishimata;Yusuke Asoh
发明人:
Shinji Marumoto,Toyoki Nishimata,Masayuki Ebisawa,Yusuke Asoh,Yasuo Fukushima,Mikio Kato
申请号:
US13059156
公开号:
US09133140B2
申请日:
2009.08.20
申请国别(地区):
US
年份:
2015
代理人:
摘要:
Provided is a therapeutic agent for hyperparathyroidism, renal osteodystrophy, hypercalcemia and the like, which has a CaSR activating (agonist) action. A compound represented by the following general formula (1):[wherein, Ar which is a partial structure in the general formula (1) represents a phenyl group or a naphthyl group; R1a and R1b are the same or different from each other, and represent a hydrogen atom, a halogeno group, or the like; R2a and R2b are the same or different from each other, and represent a hydrogen atom, a halogeno group, or the like; A represents a single bond, an oxygen atom, or the like; B represents a single bond, a C1-C4 alkanediyl group, or the like; Z represents a carboxyl group or a tetrazolyl group; and m represents an integer of 1 to 3] or a pharmacologically acceptable salt thereof.
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