ABSTRACT - 596700 Discloses a pharmaceutical composition comprising: { 1 S-[1 0, 20, 313 (1 S*,2R*),513]} -3-(7-{ [2-(3,4-difluorophenyl)cyclopropyl]amino} -5-(propylthio)-3H-1,2,3-triazolo[4,5-d]pyrimidin- 3-yl)-5-(2-hydroxyethoxy)cyclopentane-1,2-diol one or more fillers selected from mannitol, sorbitol, dibasic calcium phosphate dihydrate, dibasic calcium phosphate anhydrate and tribasic calcium phosphate or a mixture thereof one or more binders selected from alginic acid, carboxymethylcellulose sodium, copovidone and methylcellulose or a mixture thereof one or more disintegrants selected from croscarmellose sodium and crospovidone or a mixture thereof and one or more lubricants. The pharmaceutical composition disclosed has a therapeutic application in the treatment of thrombosis associated conditions.
